Since 1984, the year of the publication of its first edition, the famous "Blue Guide" has been the international reference for paediatricians and neuropaediatricians with regard to epileptic syndromes in infants, children and adolescents.
This 6th edition reviews some of the most noteworthy developments in the field, particularly in epileptic syndromes, but also focuses on the genetic aspects of the syndromes and their development. Progress brought about by advances in neuroimaging is also discussed in addition to specific etiologies such as parasitic diseases and immune and autoimmune diseases.
The different backgrounds of the contributors - coordinators and authors - ensure that the book's longstanding reputation for objectivity and seriousness, built over almost 35 years, remain well-deserved.
This book written by the current leading specialists is recognized worldwide as the international reference in epilepsy.
The health information systems of developing countries have made significant progress these last years. Nowadays, the challenge they are facing is that of their use and the acknowledgement of their usefulness by all health-systems players. Indicators at the national level would be of interest if health information systems are effectively operational.
Les études sur la biodiversité ou la mise en oeuvre de la protection intégrée impliquent d'identifier les insectes ravageurs ou les ennemis naturels.
Dans certains pays, la culture de plantes transgéniques résistantes aux chenilles, comme le cotonnier ou le maïs, risque d'entraîner une diminution de l'usage des traitements insecticides destinés à lutter contre ces ravageurs. Certaines familles de punaises comme les Pentatomidae et les Miridae sont ainsi devenues des ravageurs principaux. Il convient donc de mieux connaître ces ravageurs parfois considérés comme secondaires.
Ce guide est destiné aux personnes oeuvrant sur le terrain, agriculteurs et professionnels de l'encadrement agricole. Ils y trouveront une description brève des principales espèces de punaises phytophages et prédatrices présentes en Afrique de l'Ouest, rencontrées essentiellement sur cotonnier, maïs, niébé (Vigna unguiculata), soja et sorgho.
Chercheur passionné et naturaliste accompli, Alcide Dessalines d'Orbigny (1802-1857) a laissé une oeuvre prestigieuse et féconde dont le caractère exceptionnel, par son ampleur, ses implications dans la science actuelle et la diversité des sujets abordés, ne laisse pas d'étonner scientifiques et historiens. En présentant son premier travail sur les foraminifères (microorganismes unicellulaires, pourvus d'une coquille capable de se fossiliser), il signait l'acte de naissance de la Micropaléontologie, sans soupçonner l'importance qu'elle prendrait ensuite dans le concert des géosciences, notamment en Paléocéanographie et Paléoclimatologie, et dans le développement de la recherche pétrolière ou encore des travaux d'aménagement du territoire, tel le creusement du Tunnel sous la Manche. Les planches de foraminifères dessinés par d'Orbigny concrétisaient plusieurs années d'observation ; elles étalent destinées à l'illustration de son travail fondateur sur les foraminifères, mais restèrent inédites bien que devenues une référence incontournable pour de nombreux chercheurs. D'une grande qualité, elles témoignent des dons d'observation de leur auteur et de ses talents artistiques. Il importait donc de les publier. Elles sont reproduites dans ce volume et analysées par Marie-Thérèse Vénec-Peyré qui retrace leur histoire, replace les espèces dans le contexte scientifique actuel et fait le point sur le matériel type conservé dans les collections de Micropaléontologie du Muséum national d'Histoire naturelle.
Une monographie (en anglais) consacrée au PRP (Plasma Riche en Plaquettes) et thérapies cellulaires : les applications médicales, la fabrication, le fonctionnement, la standardisation et les études menées à ce jour avec les résultats.
La médecine régénérative englobe un large éventail de techniques ayant pour but de réparer, voire remplacer, les tissus endommagés ou âgés. Le plasma riche en plaquettes (PRP) autologue représente l'approche de médecine régénérative la plus simple. Cette technique est basée sur les capacités intrinsèques du corps humain à réparer une lésion tissulaire. L'intérêt croissant qu'elle suscite s'explique à la fois par le fait qu'elle représente une alternative sûre et naturelle à d'autres formes de traitement plus invasives et par les résultats prometteurs qu'elle a démontrés jusqu'à maintenant pour un grand nombre d'indications. Le plasma riche en plaquettes (abréviation PRP), ou plasma riche en facteurs de croissance (abréviation PRGF) est du plasma sanguin enrichi en plaquettes par une centrifugation. Le PRP est une source concentrée de plaquettes autologues. Il contient et relâche par dégranulation différents facteurs de croissance et cytokines capables de stimuler la régénération de certains tissus. Il est ainsi utilisé dans de nombreuses indications médicales et esthétiques. Si le PRP est en train de devenir un acteur incontournable dans le monde médical, certaines limitations liées à un manque de procédure standardisée pour sa préparation rendent difficile la comparaison entre les données cliniques disponibles. La technologie développée par Regen Lab SA s'impose actuellement comme la seule capable d'apporter une solution à ce défi de standardisation des préparations de cellules fraîches. Sur la base d'une expérience de plus de 10 ans, ce livre a été conçu par Regen Lab SA afin d'aider les professionnels impliqués dans la médecine régénérative à mieux comprendre et utiliser le PRP. Il est en en premier lieu destiné aux médecins qui exercent et conduisent des recherches dans des disciplines où les thérapies avec le PRP représentent une option thérapeutique, mais il s'adresse également à quiconque recherchant des informations fiables et à jour sur cette technologie.
-----
In the 60's, a scientist called Doctor Leonard Hayflick (Wistar Institute, Philadelphia) carefully characterized the serial cultivation of primary human fibroblast cell by demonstrating that primary human cell strains have a limited replicative lifespan or "doubling potential", restricted to 40-50 divisions. This finding led to the hypothesis that oxidative damage could be partially responsible for limiting in vitro lifespan, consistent with the free radical hypothesis of aging. We now know that senescence in response to repeated passage occurs because of critical shortening of the telomeres. The Hayflick theory has been greatly reconsidered by the observations from the INSERM group of Dr Barlovatz-Meimon published in 2003 in Paris regarding in vivo (i.e. on the patient himself) cell growth. These studies hypothesized that the fibroblasts may reach a 2 to 3 log growth, meaning that they could potentially undergo up to 500 to 5'000 cell divisions. Our GMP class II and III medical devices fully guarantee the patient's safety because they are non-pyrogenic. Moreover, our manufacture process respects a full compliance with the new European Medical Device Regulation (MDR) June 2017, FDA (USA), and CFDA Regulations. For all these reasons, we believe that we bring to the medical community a powerful and reliable tool to standardize PRP preparations and thus future cell therapy clinical outcomes.
Agroecology was chosen by INRAE as one of the interdisciplinary foresight projects aimed at identifying research fronts in response to major societal challenges. Eighty researchers drew up an assessment and proposed research avenues for agroecology. This book summarizes their main conclusions.
Keen to learn but short on time? Get to grips with the life of Georges Lemaître in next to no time with this concise guide.
50Minutes.com provides a clear and engaging analysis of the work of Georges Lemaître. An unlikely combination of a priest and a physicist who was responsible for the theories of the expansion of the universe and the primeval atom, which today we accept and know collectively as the Big Bang theory, Lemaître was not widely credited or recognised for his theories when he first developed them. It was not until the accidental discovery of cosmic radiation many years later that the scientific community finally came to accept this man and his ideas.
In just 50 minutes you will:
o Understand Georges Lemaître's theories of the expansion of the universe and of the primeval atom, now known as the Big Bang theory
o Find out about his life and determination to reconcile his Catholic faith with his interest in physics
o Learn about the accidental discoveries that eventually led to the confirmation of his theories
ABOUT 50MINUTES.COM | History & Culture
50MINUTES.COM will enable you to quickly understand the main events, people, conflicts and discoveries from world history that have shaped the world we live in today. Our publications present the key information on a wide variety of topics in a quick and accessible way that is guaranteed to save you time on your journey of discovery.
Find out how Amazon conquered the world in just 50 minutes!
In less than two decades, Amazon grew from a startup to become the world leader in online shopping, with hundreds of millions of customers around the world. However, the future did not always look so bright for the internet giant: its unconventional business model initially left investors worried, and it had to overcome the burst of the internet bubble that led to the collapse of many other young tech companies. In this concise and accessible guide, you will find out how Jeff Bezos was able to steer Amazon from its humble beginnings in a garage in Seattle to its current position as one of the most influential companies in the world.
In 50 minutes you will:
o Learn about Amazon's history, from 1994 right up to the present day
o Understand its innovative business model and find out why it was so successful
o Identify the opportunities and challenges for online shopping in the future
ABOUT 50MINUTES.COM | BUSINESS STORIES
The Business Stories series from the 50Minutes collection provides the tools to quickly understand the innovative companies that have shaped the modern business world. Our publications will give you contextual information, an analysis of business strategies and an introduction to future trends and opportunities in a clear and easily digestible format, making them the ideal starting point for readers looking to understand what makes these companies stand out.
The must-read summary of David Lindahl and Jonathan Rozek's book: "The Six-Figure Second Income: How to Start and Grow a Successful Online Business without Quitting Your Day Job".
This complete summary of the ideas from David Lindahl and Jonathan Rozek's book "The Six-Figure Second Income" shows how you can make a substantial income today by devoting your spare time to creating an online business. In their book, the authors explain how building and creating this business will require you to undertake different activities within three specific time frames: pre-launch, operate and optimise. This summary explains each of these stages and how you can complete them successfully in order to get your business noticed and start making a profit.
Added-value of this summary:
o Save time
o Understand key concepts
o Expand your knowledge
To learn more, read "The Six-Figure Second Income" and find out how you can use your spare time to make a substantial income online.
The must-read summary of Peter Keen and Mark McDonald's book: "The E-process Edge: Creating Customer Value and Business Wealth in the Internet Era".
This complete summary of the ideas from Peter Keen and Mark McDonald's book "The E-process Edge" shows how in order to succeed, an internet business must address three crucial issues: how to establish a good enough relationship for repeat business, how to apply competencies in the business to serve the customer and how to use the power of every network available. In their book, the authors analyse good e-processes and how you can implement them. This summary is a must-read for anyone who wants to develop the best strategy to ensure business success on the internet.
Added-value of this summary:
o Save time
o Understand key concepts
o Expand your business knowledge
To learn more, read "The E-process Edge" and discover the key to business success on the internet and how to stay ahead of the competition.
The must-read summary of Mary Modahl's book: "Now or Never: How Companies Must Change Today to Win the Battle for Internet Consumers".
This complete summary of the ideas from Mary Modahl's book "Now or Never" shows that the battle for internet consumers is still underway. It can still be won by either traditional companies or internet start-ups. However, in her book the author states that time is running out: traditional companies cannot ignore the internet for much longer and internet start-ups need to start generating profit soon. This summary presents three key objectives that companies should aim to achieve over the next five years if they want to win the battle and prosper.
Added-value of this summary:
o Save time
o Understand key concepts
o Expand your business knowledge
To learn more, read "Now or Never" and find out why it is so important for companies to gain prominence on the internet in order to survive in the future.
The must-read summary of Walid Mougayar's book: "Opening Digital Markets: Battle Plans and Business Strategies for Internet Commerce".
This complete summary of Walid Mougayar's book "Opening Digital Markets" shows that the development of Internet-based commerce is still in its early days. The implications of this development are significant for everyone, but particularly for business managers who are charged with the responsibility of successfully moving their organisations forward. In his book, the author explains how you can develop a structured strategy to exploit and fully benefit from the Internet. This summary is a must-read for planners, managers and strategists who want to achieve e-commerce success.
Added-value of this summary:
o Save time
o Understand key concepts
o Expand your business knowledge
To learn more, read "Opening Digital Markets" and find out how you can take advantage of the Internet to take your business to the next level.
The must-read summary of Gina Smith's book: "The Genomics Age: How DNA Technology Is Transforming the Way We Live and Who We Are".
This complete summary of the ideas from Gina Smith's book "The Genomics Age" shows how genetic testing is currently being used in many ways in the medical sector; however, it is experiencing challenges with costs, ethics and patient rights. In this book, the author explains the progress in genomics and what we can expect for the future. This summary provides readers with an insight into the uses and development of genomic discovery and how this will affect all of us in the years to come.
Added-value of this summary:
o Save time
o Understand key concepts
o Expand your knowledge
To learn more, read "The Genomics Age" and discover the future of genomics in medicine, criminology, academic research and the economy.
The must-read summary of Marc Ostrofsky's book: "Get Rich Click: The Ultimate Guide to Making Money on the Internet".
This complete summary of the ideas from Marc Ostrofsky's book "Get Rich Click" explains that the internet is the most powerful business tool in history because it levels the playing field. In other words, anyone with an idea and the willingness to learn what's involved can compete with large multinational firms on an equal footing. This summary highlights three essential activities that you must complete in order to make money on the internet.
Added-value of this summary:
o Save time
o Understand key concepts
o Expand your knowledge
To learn more, read "Get Rich Click" and discover the key to using the internet to turn your ideas into reality.
The must-read summary of Alan Cooper's book: "The Inmates Are Running the Asylum: Why High-Tech Products Drive Us Crazy and How to Restore the Sanity".
This complete summary of the ideas from Alan Cooper's book "The Inmates Are Running the Asylum" shows that computer technology is embedded within almost every product that is manufactured. Yet all too often, these ''new-and-improved'' products are hard to use because the engineers who are developing the interface between the user and the machine don't think like the average man-on-the-street who knows nothing about technology. Therefore, the situation effectively becomes the equivalent of letting the inmates run the asylum in which they are incarcerated. Better products need to be developed that work in the same way that average people think. Only then will new products deliver on their implied promise of enhancing the quality of life for their users. According to Alan Cooper, designers who are skilled in this specific field should be responsible for designing the interface between the user and the machine. This summary asserts that the goal of computer usage should be "not to make anyone feel stupid".
Added-value of this summary:
o Save time
o Understand the key concepts
o Increase your business knowledge
To learn more, read "The Inmates Are Running the Asylum" and rethink entrenched priorities in software planning.
The must-read summary of Frank Feather's book: "FutureConsumer.com: The Webolution of Shopping to 2010".
This complete summary of the ideas from Frank Feather's book "FutureConsumer.com" shows how the internet revolution has taken the shopping experience out of shops and into the home. This transition is set to completely transform the commercial and personal lifestyle landscape, effectively reversing everything in the industrial revolution required. In his book, the author points out that the current debate over the best approach to e-commerce is largely irrelevant. Instead, retailers should focus on winning the attention of the internet consumer, as there can only be one or two winners at most in each product category. By reading this summary, you will discover the key to coming out on top in the competitive Webolution.
Added-value of this summary:
o Save time
o Understand key concepts
o Expand your business knowledge
To learn more, read "FutureConsumer.com" and find out how you can stand out online and win the Webolution!
The must-read summary of Hank Whittemore's book: "CNN - The Inside Story: How a Band of Mavericks Changed the Face of Television News".
This complete summary of the ideas from Hank Whittemore's book "CNN - The Inside Story" tells the story behind the creation of television station Cable News Network and its founder, Ted Turner. In his book, Hank Whittemore describes the risks Turner took and how he tried to take over CBS and fought against ABC. This summary contains inspiring quotes and an interesting behind-the-scenes look at one of the most successful television channels.
Added-value of this summary:
o Save time
o Understand key concepts
o Expand your knowledge
To learn more, read "CNN - The Inside Story" and discover the story behind the channel and the risks it took to create it.
This guide is intended to be practical and accessible to all actors of the upstream, midstream oil & gas sectors, it is intended primarily for use by operators, inspectors, technologists, engineering companies, suppliers of equipment and anticorrosion solutions and those responsible for corrosion and erosion control in the sectors of exploration production (upstream) of mineral oils, natural gas and Liquefied Natural Gas.
The main objectives are:
o to promote awareness of the damage mechanisms that are commonly occurring oil and gas
production facilities for all persons involved;
o to indicate their potential severity, according to the operating conditions;
o to help locate these mechanisms in the facilities, in order to anticipate them, avoid them or monitor
their evolution;
o to help with materials selection and corrosion prevention solutions in the design phase;
o to provide schematics and diagrams that can be use in documents, guides, specifications, ...;
o to provide up-to-date feedback from operated facilities.
This guide consists of four sections: 1 - contextual presentation and objectives; 2 - definitions, standards; 3 - reminders on the feared damage mechanisms in the upstream sector; 4 - prediction of corrosion in upstream facilities.
The third section describes the degradation mechanisms encountered in the upstream and midstream, thirteen specific mechanisms are identified while in the last section, the possible damage mechanisms, their severity, and location are described for ten process units and ten utility units. The descriptions are illustrated in typical Corrosion Prediction Diagrams and Material Selection Diagrams. Typical material selection and prevention solutions are provided. They are also reported and described on these same diagrams. These proposals are generic, should be considered as a guideline, and have to be confirmed or infirmed during detailed engineering studies.
Attractive, entertaining, and educational: the Visual Dictionary of the Human Body is an indispensable family reference, and a great tool to acquire vocabulary and discover the complexity of the human body.
Some species prefer to live alone, and others like company. Social animals form groups such as clans or schools and use their combined strength to fight enemies, cold or boredom. Their giant gatherings can last for a few hours, a few days or even a few years. Secret societies are revealed, explained and illustrated, to help you better understand the social lives of animals.
How do animals seduce each other? How are baby animals conceived? What do they look like when they're born? These are just some of the questions answered in the colorful and fascinating pages of this book. From the parents' first date to the arrival of the little ones, leaf through the family album of the animal world and discover the often unusual stories of some very astonishing species.
The world of plants is astoundingly diverse. Thanks to 3 billion years of evolution, there are now more than 380,000 plant species on Earth.
For all curious readers, the Knowledge Guides open the door to a world of complex and captivating phenomena.
Accurate, detailed visual information is all defined in lay language to make it readily accessible to the non-expert. Definitions to scientific terms are given either in the explanation itself, or in the comprehensive glossary.
