The first full biography of Britain's leading actress of her time.
Whether it is her sunny temperament, her gift of laughter, her wide-ranging abilities, or all three, Judi Dench is without doubt a star. Shortlisted for a 1998 Oscar for her performance as Queen Victoria in MRS BROWN, she then won one for her role as Queen Elizabeth in SHAKESPEARE IN LOVE. Judi Dench is widely loved, and not only among the theatrical profession. Her long-running appearance opposite Geoffrey Palmer in the TV situation comedy AS TIME GOES BY has run to four series and gained her a TV TIMES readers' award as ¿the actress we most wish see more often on television¿. She juggles the National Theatre (a sell-out season in Sondheim's A LITTLE NIGHT MUSIC and David Hare's AMY'S VIEW) with TV and films (she is now established as 'M' in the latest James Bond series).
Since the paperback edition was published, John Miller has written a new chapter, bringing what is fast becoming a classic biography completely up-to-date.
Découvrez le récit des origines de Daredevil : son enfance, l'accident qui l'a rendu aveugle et le destin tragique de son père. Assistez également à ses premiers affrontements avec le Caïd, ainsi qu'à sa rencontre avec Elektra. Frank Miller et John Romita Jr vous dévoilent tout ce qu'il faut savoir sur Matt Murdock dans une saga qui a inspiré la série Netflix.
Les Avengers se font attaquer par l'un des leurs et tombent les uns après les autres. Captain America et ses coéquipiers ne savent pas qui est le traître mais ils sont frappés par quelqu'un qui connaît tous leurs secrets et points faibles... Serait-ce la fin des Avengers ? Découvrez ce récit renversant écrit par Brian M. Bendis (House of M) et illustré par David Finch (New Avengers) ainsi que de nombreux dessinateurs invités.
An -11. Le prequel à la série TV Star Wars Rebels. AN -11
Depuis que les Jedi ont été condamnés à mort et contraints de quitter Coruscant, Kanan Jarrus s'est consacré à sa propre survie plutôt qu'à servir la Force. Il voyage seul à travers la galaxie, passant d'un emploi anonyme à l'autre, et évite les ennuis. Bien qu'un conflit meurtrier vienne d'éclater entre les Forces Impériales et quelques révolutionnaires désespérés, il se garde de toute action. Mais l'Empire tue brutalement un de ses amis, l'ancien Jedi doit choisir : céder à la panique ou combattre. Jarrus cependant n'affrontera pas seul l'Empire. Des alliés inattendus le rejoignent et ensemble ils devront faire front contre l'un des plus redoutables émissaires de l'Empereur...
An - 19. La République a sombré, emportée par le côté obscur. L'Empire règne sur la galaxie, aux mains des Seigneurs Sith. Le Maître Jedi Obi-Wan Kenobi a tout perdu. Mais sur Tatooine, grandit un espoir...Star Wars légendes - n°131 An - 19 Les Sith règnent sur la galaxie. Le Maître Jedi Obi-Wan Kenobi a tout perdu...
Sauf l'espoir. Et celui-ci grandit sur Tatooine - planète désertique, écrasée par la chaleur de deux soleils. Ici, tout le monde connaît le vieux Ben, mais personne ne sait vraiment qui est ce mystérieux ermite. Lorsque des fermiers sont attaqués par une bande de redoutables Hommes des Sables, le vieux Ben est obligé de sortir de sa retraite.
Car maîtriser la Force implique de lourdes responsabilités. Au risque de révéler son identité, le Maître Jedi Obi-Wan Kenobi n'a pas d'autre choix que de mener un nouveau combat.
Epilepsy is common but complex
Epilepsy is a complicated neurological condition with variable manifestations, numerous etiologies, and a diverse range of treatments. It is a chronic disease that, in many cases, can be controlled. However, treatment requires accurate clinical evaluation to allow intelligent treatment choices. Epilepsy has been designed to help you develop these evaluation skills. Expert neurologists have distilled the evidence and combined their experience. They provide practical guidance to: The causes and classification of epilepsy Working up seizures Antiepileptic medications Pediatric epilepsy Adult epilepsy Emergency epilepsy Comorbidity and mortality of epilepsy Clinical in approach, practical in execution, Epilepsy is packed with tricks, tips, and focused advice to help you better manage your patients' seizures.
A Handbook to the Reception of Ovid presents more than 30 original essays written by leading scholars revealing the rich diversity of critical engagement with Ovid's poetry that spans the Western tradition from antiquity to the present day. Offers innovative perspectives on Ovid's poetry and its reception from antiquity to the present day Features contributions from more than 30 leading scholars in the Humanities. Introduces familiar and unfamiliar figures in the history of Ovidian reception. Demonstrates the enduring and transformative power of Ovid's poetry into modern times.
2004 Arthur Ellis Award Nominee. Is it a crime to try to pick an empty pocket? Miller covers a wide range of legal history in this entertaining book that explores the unusual side of the law, which the public often doesn't hear about.
This work is a collection of Carl Wenicke's lectures on neuropsychiatry translated into English for the first time. Beginning with basic concepts about normal brain function, the book moves to clinical topics, dealing first with chronic mental disorders and 'paranoid states', and then to the more complex area of acute mental disorders. Many of the featured topics are still clinically relevant, and matters of contemporary debate. Carl Wernicke is one of the pioneers of neurology and psychiatry; clinicians, researchers and historians will find this of great interest.
In the first attempt to fully explore the controversial issues associated with the commercial application of nanotechnology, you'll find a thorough analysis of intellectual property and patents, financing and legal concerns, regulatory measures particularly in the field of nanomedicine, and environmental regulations. The authors include a set of guideposts you can follow in your due diligence of the business and legal issues pertaining to the technology.
Addiction Research Methods' is a comprehensive handbook for health professionals, policy-makers and researchers working and training in the field of addiction. The book provides a clear, comprehensive and practical guide to research design, methods and analysis within the context of the field of alcohol and other drugs. The reader is introduced to fundamental principles and key issues; and is orientated to available sources of information and key literature. Written by a team of internationally acclaimed contributors, the book is divided into six major sections: Introduction; Research Design; Basic Toolbox; Biological Models; Specialist Methods; and Analytical Methods. Each chapter offers an introduction to the background and development of the discipline in question, its key features and applications, how it compares to other methods/analyses and its advantages and limitations. FEATURES List of useful websites and assistive technology. Case study examples List of useful hermeneutics Recommended reading list Contains exercises to help the reader to develop their skills.
There have been rapid developments in the psychological management of sexually transmitted diseases, particularly HIV and AIDS. However, a significant proportion of those attending genitourinary clinics do not have a disease or infection, but rather are seeking help with sexual health issues relating to behaviour, prior sexual experiences and relationships. Hence as clinics become more and more generalist there is a need to focus on behavioural aspects of disease. This is the first text to draw together the knowledge base and expertise of clinicians and researchers from all disciplines in the psychological management of sexual health. It presents advances in theory and practice in a practical way that will be accessible for all disciplines.
The only text to cover lung function assessment from first principles including methodology, reference values and interpretation New for this edition:
- More illustrations to convey concepts clearly to the busy physician - Text completely re-written in a contemporary style: includes user-friendly equations and more diagrams - New material covering the latest advances in the treatment of lung function, including more on sleep-related disorders, a stronger clinical and practical bias and more on new techniques and equipment - Uses the standard Vancouver referencing system
What the experts say: "I have always considered Dr Cotes' book the most authoritative book published on lung function. It is also the most comprehensive."
-Dr Robert Crapo, Pulmonary Division, LDS Hospital, Salt Lake City, USA "I think I can fairly speak on behalf of staff in lung function departments the length and breadth of the country - that a sixth edition of Cotes would be gratefully received."
-Dr Brendan Cooper, Clinical Respiratory Scientist, Nottingham City Hospital
The Matching Method for Asymptotic Solutions in Chemical PhysicsProblems by A. M. Il'in, L. A. Kalyakin, and S. I.Maslennikov
Singularly Perturbed Problems with Boundary and Interior Layers:Theory and Application by V. F. Butuzov and A. B. Vasilieva
Numerical Methods for Singularly Perturbed Boundary Value ProblemsModeling Diffusion Processes by V. L. Kolmogorov and G. I.Shishkin
An important addition to the Advances in Chemical Physics series,this volume makes available for the first time in English the workof leading Russian researchers in singular perturbation theory andits application. Since boundary layers were first introduced byPrandtl early in this century, rapid advances have been made in theanalytic and numerical investigation of these phenomena, andnowhere have these advances been more notable than in the Russianschool of singular perturbation theory. The three chapters in thisvolume treat various aspects of singular perturbations and theirnumerical solution, and represent some of the best work done inthis area:
* The first chapter, "The Matching Method for Asymptotic Solutionsin Chemical Physics Problems," is concerned with the analysis ofsome singular perturbation problems that arise in chemicalkinetics. In this chapter the matching method is applied to findasymptotic solutions to some dynamical systems of ordinarydifferential equations whose solutions have multiscale timedependence.
* The second chapter, "Singularly Perturbed Problems with Boundaryand Interior Layers: Theory and Application," offers acomprehensive overview of the theory and application of asymptoticapproximations for many different kinds of problems in chemicalphysics governed by either ordinary or partial differentialequations with boundary and interior layers.
* The third chapter, "Numerical Methods for Singularly PerturbedBoundary Value Problems Modeling Diffusion Processes," discussesthe numerical difficulties that arise in solving the problemsdescribed in the first two chapters, and proposes rigorous criteriafor determining whether or not a numerical method is satisfactoryfor such problems. Methods satisfying these criteria are thenconstructed and applied to obtain numerical solutions to a range ofsample problems.
Timely, authoritative, and invaluable to researchers in all areasof chemical physics, Singular Perturbation Problems in ChemicalPhysics is an essential resource.
This practical book describes a systematic approach to the ultrasound examination of the fetal heart based on accepted screening recommendations. The written content is enhanced by images and videos of both normal and abnormal sonographic findings. Fetal Cardiology: A Practical Approach to Diagnosis and Management goes further than simply describing core screening views. It includes extended views of the fetal heart, the use of Doppler techniques and assessment of fetal cardiac function. "Variants" which can be encountered in practice are described as well as the features of the major groups of cardiac abnormalities and fetal arrhythmias. Because the authors include experienced fetal and paediatric cardiologists, the focus is not only on diagnostic features but also the approach to postnatal care and prognosis. This content is enhanced by inclusion of chapters relating to associated fetal abnormalities, the genetics of congenital heart disease and new imaging modalities such as MRI of the fetal heart. The book equips all those using ultrasound to image the fetus with a clear concise reference to meet the challenge of new guidelines and to expand their knowledge of complementary echocardiographic techniques and management. It details why prenatal recognition of congenital heart disease is being prioritised to allow for parental choice, recognition of associated abnormalities and improvement of postnatal outcome. As such, this book will be important for all professionals, whether they be a cardiologist, fetal medicine specialist, sonographer or midwife.
Adopting a practical approach, the authors provide a detailed interpretation of the existing regulations (GMP, ICH), while also discussing the appropriate calculations, parameters and tests. The book thus allows readers to validate the analysis of pharmaceutical compounds while complying with both the regulations as well as the industry demands for robustness and cost effectiveness.
Following an introduction to the basic parameters and tests in pharmaceutical validation, including specificity, linearity, range, precision, accuracy, detection and quantitation limits, the text focuses on a life-cycle approach to validation and the integration of validation into the whole analytical quality assurance system. The whole is rounded off with a look at future trends.
With its first-hand knowledge of the industry as well as regulating bodies, this is an invaluable reference for analytical chemists, the pharmaceutical industry, pharmaceutists, QA officers, and public authorities.
Tested-in-the-trenches competitive intelligence techniques used at today's top companies This book brings together the best thinking and practices in competitive intelligence (CI) currently being used at many of today's most successful companies. Featuring contributions from leading industry executives, it covers CI strategies across a wide range of business functions, including marketing and sales, market research and forecasting, product development, and teams. The only book on the subject offering a comprehensive view of CI, from the CEO down to the tactical CI team Numerous case studies vividly illustrating cutting-edge CI techniques in action
This Brief explores emerging trends in drug use and distribution. This timely Brief examines recent examples of emerging drugs including salvia (from the plant Salvia divinorum), bath salts (and other synthetic stimulants) and so-called research chemicals (primarily substituted phenethylamines, synthetic cousins of ecstasy), which have tended to receive brief levels of high intensity media coverage that may or may not reflect an actual increase in their usage. Over the past decade in particular, "new" substances being used recreationally seem to come out of obscurity and gain rapid popularity, particularly spurred on by discussion and distribution over the internet. While changing trends in the drug market have always presented a challenge for law enforcement and public health officials, online forums, media coverage and other recent trends discussed in this Brief allow them to gain popularity more quickly and change more frequently. These rapid shifts allow less time for researchers to understand the potential health consequences of these substances and for law enforcement to stay abreast of abuses of legal substances. This work includes: 1) review of relevant research and literature, 2) review the Internet sources in which many deem important in influencing the emerging drug market, 3) discussion of national and international trends in use, abuse and distribution of these substances and 4) examination of current drug policy and recommendations for the future. This brief will be useful for criminology and criminal justice, sociology and public health. It will also be useful for those that deal with youth and the problems that may develop during adolescence and early adulthood.
This volume is the first comprehensive guide to current research on animals, animality, and human-animal relations in literature. To reflect the history of literary animal studies to date, its primary focus is literary prose and poetry in English, while also accommodating emergent discussions of the full range of media and contexts with which literary studies engages, especially film and critical theory. User-friendly language, references, even suggestions for further readings are included to help newcomers to the field understand how it has taken shape primarily through recent decades. To further aid teachers, sections are organized by conventions of periodization, and chapters address a range of canonical and popular texts. Bookended by sections devoted to the field's conceptual foundations and new directions, the volume is designed to set an agenda for literary animal studies for decades to come.
It is widely acknowledged that life has adapted to its environment, but the precise mechanism remains unknown since Natural Selection, Descent with Modification and Survival of the Fittest are metaphors that cannot be scientifically tested. In this unique text, invertebrate and vertebrate biologists illuminate the effects of physiologic stress on epigenetic responses in the process of evolutionary adaptation from unicellular organisms to invertebrates and vertebrates, respectively. This book offers a novel perspective on the mechanisms underlying evolution.Capacities for morphologic alterations and epigenetic adaptations subject to environmental stresses are demonstrated in both unicellular and multicellular organisms. Furthermore, the underlying cellular-molecular mechanisms that mediate stress for adaptation will be elucidated wherever possible. These include examples of `reverse evolution' by Professor Guex for Ammonites and for mammals by Professor Torday and Dr. Miller. This provides empiric evidence that the conventional way of thinking about evolution as unidirectional is incorrect, leaving open the possibility that it is determined by cell-cell interactions, not sexual selection and reproductive strategy. Rather, the process of evolution can be productively traced through the conservation of an identifiable set of First Principles of Physiology that began with the unicellular form and have been consistently maintained, as reflected by the return to the unicellular state over the course of the life cycle.
This book examines the many ethical issues that are encountered in the Pediatric Intensive Care Unit (PICU). It supports pediatricians, nurses, residents, and other providers in their daily management of critically ill children with the dilemmas that arise. It begins by examining the evolution of pediatric critical care, and who is now impacted by this advancing medical technology. Subsequent chapters explore specific ethical concerns and controversies that are commonly encountered. These topics include how to conduct end-of-life discussions with families facing a myriad of challenging choices. It goes on to explore the concept of futility, and what that does and does not mean in the pediatric ICU setting. Controversial subjects such as children as organ donors, particularly using donation after cardiac death, in addition to issues surrounding the declaration of brain death are covered. Additional chapters address resource allocation, and also analyze the use of long-term technology in chronically critically ill children. Chapters include case examples with guidance on how to work through similar difficulties and decision-making. While this book is specifically targeted for care providers at the ICU bedside, it is also of benefit to medical students, students in bioethics, practicing ethical consultants and families who are dealing with critically ill children.
Human resources are led, not managed. Supervision in the Hospitality Industry: Leading Human Resources, Sixth Edition is about leading the people who cook, serve, tend bar, check guests in and out, carry bags, clean rooms, mop floors-the people on whom success or failure of every hospitality enterprise depends. It is a book about first-line supervision, written especially for the beginning leader, newly promoted supervisor, or anyone planning a career in the hospitality field. Even experienced managers will find if full of useful ideas and insights. Revised and updated to include increased coverage of contemporary diversity initiatives, with information on recruitment and retention, and additional profiles of individuals and companies, Supervision in the Hospitality Industry provides a basic understanding of a leader's role and responsibilities applied to the hospitality industry.
This collection of essays centers on literary representations of meat-eating, bringing aesthetic questions into dialogue with more established research on the ethics and politics of meat. From the decline of traditional animal husbandry to the emergence of intensive agriculture and the biotechnological innovation of in vitro meat, the last hundred years have seen dramatic changes in meat production. Meat consumption has risen substantially, inciting the emergence of new forms of political subjectivity, such as the radical rejection of meat production in veganism. Featuring essays on both canonical and lesser-known authors, Literature and Meat Since 1900 illustrates the ways in which our meat regime is shaped, reproduced and challenged as much by cultural and imaginative factors as by political contestation and moral reasoning.
There has been no mechanistic explanation for evolutionary change consistent with phylogeny in the 150 years since the publication of `Origins'. As a result, progress in the field of evolutionary biology has stagnated, relying on descriptive observations and genetic associations rather testable scientific measures.
This book illuminates the need for a larger evolutionary-based platform for biology. Like physics and chemistry, biology needs a central theory in order to frame the questions that arise, the way hypotheses are tested, and how to interpret the data in the context of a continuum.The reduction of biology to its self-referential, self-organized properties provides the opportunity to recognize the continuum from the Singularity/Big Bang to Consciousness based on cell-cell communication for homeostasis.
